BDBM50276409 (1S,2S)-N-(2-methoxyethyl)-2-(thiophen-3-yl)-1,2,3,4-tetrahydronaphthalen-1-amine::CHEMBL512394

SMILES COCCN[C@H]1[C@@H](CCc2ccccc12)c1ccsc1

InChI Key InChIKey=XFZOACPROGGFGC-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50276409   

TargetMu-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276409((1S,2S)-N-(2-methoxyethyl)-2-(thiophen-3-yl)-1,2,3...)
Affinity DataIC50: 5.30nMAssay Description:Displacement of [125I]FK33824 from human cloned mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276409((1S,2S)-N-(2-methoxyethyl)-2-(thiophen-3-yl)-1,2,3...)
Affinity DataIC50: 707nMAssay Description:Displacement of [125I]U69593 from human cloned kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276409((1S,2S)-N-(2-methoxyethyl)-2-(thiophen-3-yl)-1,2,3...)
Affinity DataEC50:  2.60E+3nMAssay Description:Agonist activity at human cloned mu opioid receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276409((1S,2S)-N-(2-methoxyethyl)-2-(thiophen-3-yl)-1,2,3...)
Affinity DataIC50: 3.80E+3nMAssay Description:Displacement of [125I]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276409((1S,2S)-N-(2-methoxyethyl)-2-(thiophen-3-yl)-1,2,3...)
Affinity DataIC50: 1.90E+4nMAssay Description:Activity at human cloned mu opioid receptor assessed as reversal of DAMGO-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed