BDBM50276412 (+/-)-3,4-dichloro-N-(2-methoxyethyl)-N-(2-(4-phenylpiperazin-1-yl)-1,2-dihydronaphthalen-1-yl)benzamide::CHEMBL460832

SMILES COCCN(C1C(C=Cc2ccccc12)N1CCN(CC1)c1ccccc1)C(=O)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=DAGRHBYUCYVLNY-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50276412   

TargetMu-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276412((+/-)-3,4-dichloro-N-(2-methoxyethyl)-N-(2-(4-phen...)
Affinity DataIC50: 443nMAssay Description:Displacement of [125I]FK33824 from human cloned mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276412((+/-)-3,4-dichloro-N-(2-methoxyethyl)-N-(2-(4-phen...)
Affinity DataIC50: 3.62E+3nMAssay Description:Displacement of [125I]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276412((+/-)-3,4-dichloro-N-(2-methoxyethyl)-N-(2-(4-phen...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]U69593 from human cloned kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276412((+/-)-3,4-dichloro-N-(2-methoxyethyl)-N-(2-(4-phen...)
Affinity DataEC50: >9.00E+4nMAssay Description:Activity at human cloned mu opioid receptor assessed as reversal of DAMGO-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed