BDBM50276458 2-(Aminomethyl)-5-(1'-naphthyl)tetrahydrofuran::CHEMBL456638

SMILES NCC1CCC(O1)c1cccc2ccccc12

InChI Key InChIKey=HDLNQDARKJUPIY-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50276458   

TargetSodium-dependent serotonin transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50276458(2-(Aminomethyl)-5-(1'-naphthyl)tetrahydrofuran | C...)
Affinity DataIC50: 24nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50276458(2-(Aminomethyl)-5-(1'-naphthyl)tetrahydrofuran | C...)
Affinity DataKi:  174nMAssay Description:Displacement of [125I]RTI55 from human SERT expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50276458(2-(Aminomethyl)-5-(1'-naphthyl)tetrahydrofuran | C...)
Affinity DataIC50: 210nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50276458(2-(Aminomethyl)-5-(1'-naphthyl)tetrahydrofuran | C...)
Affinity DataIC50: 463nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50276458(2-(Aminomethyl)-5-(1'-naphthyl)tetrahydrofuran | C...)
Affinity DataKi:  1.49E+3nMAssay Description:Displacement of [125I]RTI55 from human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50276458(2-(Aminomethyl)-5-(1'-naphthyl)tetrahydrofuran | C...)
Affinity DataKi:  8.52E+3nMAssay Description:Displacement of [125I]RTI55 from human DAT expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed