BDBM50276459 2-(Aminomethyl)-5-phenethyltetrahydrofuran::CHEMBL456639

SMILES NCC1CCC(CCc2ccccc2)O1

InChI Key InChIKey=LKTJWDXCFJJUGY-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50276459   

TargetSodium-dependent serotonin transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50276459(2-(Aminomethyl)-5-phenethyltetrahydrofuran | CHEMB...)
Affinity DataKi:  68nMAssay Description:Displacement of [125I]RTI55 from human SERT expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50276459(2-(Aminomethyl)-5-phenethyltetrahydrofuran | CHEMB...)
Affinity DataIC50: 129nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50276459(2-(Aminomethyl)-5-phenethyltetrahydrofuran | CHEMB...)
Affinity DataIC50: 360nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50276459(2-(Aminomethyl)-5-phenethyltetrahydrofuran | CHEMB...)
Affinity DataIC50: 513nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50276459(2-(Aminomethyl)-5-phenethyltetrahydrofuran | CHEMB...)
Affinity DataKi:  1.51E+3nMAssay Description:Displacement of [125I]RTI55 from human DAT expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50276459(2-(Aminomethyl)-5-phenethyltetrahydrofuran | CHEMB...)
Affinity DataKi:  2.74E+3nMAssay Description:Displacement of [125I]RTI55 from human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed