BDBM50276497 (+/-)-2-(4-chlorophenoxy)-N-(2-(dimethylamino)-6,7-dimethoxy-1,2,3,4-tetrahydronaphthalen-1-yl)-N-(2-methoxyethyl)acetamide::CHEMBL461257

SMILES COCCN(C1C(CCc2cc(OC)c(OC)cc12)N(C)C)C(=O)COc1ccc(Cl)cc1

InChI Key InChIKey=URNXZPMTXANSSI-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50276497   

TargetKappa-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276497((+/-)-2-(4-chlorophenoxy)-N-(2-(dimethylamino)-6,7...)
Affinity DataIC50: 155nMAssay Description:Displacement of [125I]U69593 from human cloned kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276497((+/-)-2-(4-chlorophenoxy)-N-(2-(dimethylamino)-6,7...)
Affinity DataIC50: 245nMAssay Description:Displacement of [125I]FK33824 from human cloned mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276497((+/-)-2-(4-chlorophenoxy)-N-(2-(dimethylamino)-6,7...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]deltorphin 2 from human cloned delta opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50276497((+/-)-2-(4-chlorophenoxy)-N-(2-(dimethylamino)-6,7...)
Affinity DataEC50: >9.00E+4nMAssay Description:Agonist activity at human cloned mu opioid receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed