BDBM50276591 CHEMBL511500::trans-2-(Aminomethyl)-5-(2'-methoxy-5'-fluorophenethyl)tetrahydrofuran

SMILES COc1ccc(F)cc1CC[C@H]1CC[C@H](CN)O1

InChI Key InChIKey=CLSUYIGLXGEXLU-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50276591   

TargetSodium-dependent serotonin transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50276591(trans-2-(Aminomethyl)-5-(2'-methoxy-5'-fluorophene...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50276591(trans-2-(Aminomethyl)-5-(2'-methoxy-5'-fluorophene...)
Affinity DataKi:  3.20nMAssay Description:Displacement of [125I]RTI55 from human SERT expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50276591(trans-2-(Aminomethyl)-5-(2'-methoxy-5'-fluorophene...)
Affinity DataIC50: 628nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50276591(trans-2-(Aminomethyl)-5-(2'-methoxy-5'-fluorophene...)
Affinity DataKi:  5.99E+3nMAssay Description:Displacement of [125I]RTI55 from human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50276591(trans-2-(Aminomethyl)-5-(2'-methoxy-5'-fluorophene...)
Affinity DataIC50: 8.56E+3nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50276591(trans-2-(Aminomethyl)-5-(2'-methoxy-5'-fluorophene...)
Affinity DataKi:  1.45E+4nMAssay Description:Displacement of [125I]RTI55 from human DAT expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed