BDBM50276642 CHEMBL460407::trans-2-Aminomethyl-5-((2''-methoxy-5''-fluorophenyl)-3'-propyl)tetrahydrofuran

SMILES COc1ccc(F)cc1CCC[C@H]1CC[C@H](CN)O1

InChI Key InChIKey=BWBCTVUBHWYIEP-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50276642   

TargetSodium-dependent serotonin transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50276642(trans-2-Aminomethyl-5-((2''-methoxy-5''-fluorophen...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [125I]RTI55 from human SERT expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50276642(trans-2-Aminomethyl-5-((2''-methoxy-5''-fluorophen...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50276642(trans-2-Aminomethyl-5-((2''-methoxy-5''-fluorophen...)
Affinity DataIC50: 2.93E+3nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50276642(trans-2-Aminomethyl-5-((2''-methoxy-5''-fluorophen...)
Affinity DataKi:  7.33E+3nMAssay Description:Displacement of [125I]RTI55 from human DAT expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50276642(trans-2-Aminomethyl-5-((2''-methoxy-5''-fluorophen...)
Affinity DataIC50: 7.62E+3nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50276642(trans-2-Aminomethyl-5-((2''-methoxy-5''-fluorophen...)
Affinity DataKi:  8.54E+3nMAssay Description:Displacement of [125I]RTI55 from human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed