BDBM50276653 (S)-2-(4-(((S)-1-((R)-3-amino-4-(2,5-difluorophenyl)butanoyl)pyrrolidine-2-carboxamido)methyl)phenoxy)-3-methylbutanoic acid 2,2,2-trifluoroacetic acid::CHEMBL445949

SMILES CC(C)[C@H](Oc1ccc(CNC(=O)[C@@H]2CCCN2C(=O)C[C@H](N)Cc2cc(F)ccc2F)cc1)C(O)=O

InChI Key InChIKey=GERHAXJHCLVDBJ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50276653   

TargetDipeptidyl peptidase 4(Human)
Bristol Myers Squibb Research and Early Development

Curated by ChEMBL
LigandPNGBDBM50276653((S)-2-(4-(((S)-1-((R)-3-amino-4-(2,5-difluoropheny...)
Affinity DataIC50: 0.480nMAssay Description:Inhibition of recombinant human dipeptidyl peptidase 4 using Gly-Pro-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Human)
Bristol Myers Squibb Research and Early Development

Curated by ChEMBL
LigandPNGBDBM50276653((S)-2-(4-(((S)-1-((R)-3-amino-4-(2,5-difluoropheny...)
Affinity DataIC50: 0.480nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase FAP(Human)
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50276653((S)-2-(4-(((S)-1-((R)-3-amino-4-(2,5-difluoropheny...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of FAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50276653((S)-2-(4-(((S)-1-((R)-3-amino-4-(2,5-difluoropheny...)
Affinity DataIC50: 7.60E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50276653((S)-2-(4-(((S)-1-((R)-3-amino-4-(2,5-difluoropheny...)
Affinity DataIC50: 8.60E+4nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50276653((S)-2-(4-(((S)-1-((R)-3-amino-4-(2,5-difluoropheny...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of QPPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50276653((S)-2-(4-(((S)-1-((R)-3-amino-4-(2,5-difluoropheny...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed