BDBM50276988 2-(4-methylpiperazin-1-yl)-4-(naphthalen-1-ylsulfonyl)benzo[d]oxazole::CHEMBL459988

SMILES CN1CCN(CC1)c1nc2c(cccc2o1)S(=O)(=O)c1cccc2ccccc12

InChI Key InChIKey=VRQZVFGHYLFLHY-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50276988   

Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50276988(2-(4-methylpiperazin-1-yl)-4-(naphthalen-1-ylsulfo...)
Affinity DataKi:  9.70nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50276988(2-(4-methylpiperazin-1-yl)-4-(naphthalen-1-ylsulfo...)
Affinity DataIC50: 105nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells assessed as blockage of 5-HT-stimulated cAMP formation after 10 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed