BDBM50277045 CHEMBL459350::[3-(10,11-Dihydro-dibenzo[a,d]cyclohepten-5-ylidene)-propyl]-methyl-[4-(3-piperidin-1-yl-propoxy)-benzyl]-amine

SMILES [#6]-[#7](-[#6]-[#6]\[#6]=[#6]-1/c2ccccc2-[#6]-[#6]-c2ccccc-12)-[#6]-c1ccc(-[#8]-[#6]-[#6]-[#6]-[#7]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)cc1

InChI Key InChIKey=IFHQDBJYTRZYIK-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50277045   

TargetHistamine H3 receptor(Human)
Johann Wolfgang Goethe Universit£T

Curated by ChEMBL
LigandPNGBDBM50277045([3-(10,11-Dihydro-dibenzo[a,d]cyclohepten-5-yliden...)
Affinity DataKi:  0.25nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in CHO/HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Johann Wolfgang Goethe Universit£T

Curated by ChEMBL
LigandPNGBDBM50277045([3-(10,11-Dihydro-dibenzo[a,d]cyclohepten-5-yliden...)
Affinity DataKi:  67nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Johann Wolfgang Goethe Universit£T

Curated by ChEMBL
LigandPNGBDBM50277045([3-(10,11-Dihydro-dibenzo[a,d]cyclohepten-5-yliden...)
Affinity DataKi:  79nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Johann Wolfgang Goethe Universit£T

Curated by ChEMBL
LigandPNGBDBM50277045([3-(10,11-Dihydro-dibenzo[a,d]cyclohepten-5-yliden...)
Affinity DataKi:  101nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
Johann Wolfgang Goethe Universit£T

Curated by ChEMBL
LigandPNGBDBM50277045([3-(10,11-Dihydro-dibenzo[a,d]cyclohepten-5-yliden...)
Affinity DataKi:  273nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D5 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Johann Wolfgang Goethe Universit£T

Curated by ChEMBL
LigandPNGBDBM50277045([3-(10,11-Dihydro-dibenzo[a,d]cyclohepten-5-yliden...)
Affinity DataKi:  305nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed