BDBM50277064 4-(quinolin-4-ylmethylamino)-N-(3-(trifluoromethyl)phenyl)isothiazole-3-carboxamide::CHEMBL458531
SMILES FC(F)(F)c1cccc(NC(=O)c2nscc2NCc2ccnc3ccccc23)c1
InChI Key InChIKey=BWOICBFNIQMBIO-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50277064
Affinity DataIC50: 110nMAssay Description:Inhibition of VEGFR2 assessed as blockade of pGAT-biotin phosphorylation in presence of 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 390nMAssay Description:Inhibition of VEGFR2 expressed in HEK293 cells assessed as inhibition of receptor phosphorylation by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 580nMAssay Description:Inhibition of VEGFR1 assessed as blockade of pGAT-biotin phosphorylation in presence of 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair
