BDBM50277077 CHEMBL517407::{3-[2-Chloro-thioxanthenylidene]-propyl}-methyl-[4-(3-piperidin-1-yl-propoxy)-benzyl]-amine

SMILES CN(CC\C=C1/c2ccccc2Sc2ccc(Cl)cc12)Cc1ccc(OCCCN2CCCCC2)cc1

InChI Key InChIKey=DSRXHDAICZGTCK-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50277077   

TargetHistamine H3 receptor(Human)
Johann Wolfgang Goethe Universit£T

Curated by ChEMBL
LigandPNGBDBM50277077({3-[2-Chloro-thioxanthenylidene]-propyl}-methyl-[4...)
Affinity DataKi:  1.54nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in CHO/HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Johann Wolfgang Goethe Universit£T

Curated by ChEMBL
LigandPNGBDBM50277077({3-[2-Chloro-thioxanthenylidene]-propyl}-methyl-[4...)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Johann Wolfgang Goethe Universit£T

Curated by ChEMBL
LigandPNGBDBM50277077({3-[2-Chloro-thioxanthenylidene]-propyl}-methyl-[4...)
Affinity DataKi:  52nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Johann Wolfgang Goethe Universit£T

Curated by ChEMBL
LigandPNGBDBM50277077({3-[2-Chloro-thioxanthenylidene]-propyl}-methyl-[4...)
Affinity DataKi:  248nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Johann Wolfgang Goethe Universit£T

Curated by ChEMBL
LigandPNGBDBM50277077({3-[2-Chloro-thioxanthenylidene]-propyl}-methyl-[4...)
Affinity DataKi:  295nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
Johann Wolfgang Goethe Universit£T

Curated by ChEMBL
LigandPNGBDBM50277077({3-[2-Chloro-thioxanthenylidene]-propyl}-methyl-[4...)
Affinity DataKi:  297nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D5 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed