BDBM50277169 CHEMBL4166735

SMILES [H][C@@]12CC[C@]3([H])[C@]([H])(CC[C@]4(C)[C@H]([C@H](O)C[C@]34O)C3=CC(=O)OC3)[C@]1(C[C@@]1([H])O[C@]3(O)[C@@]([H])(O[C@H](C)C[C@]33SCC=N3)O[C@]1([H])C2)C=O

InChI Key InChIKey=WHPLQBQPUGBPJI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50277169   

TargetNeurogenic locus notch homolog protein 1(Human)
Chiba University

Curated by ChEMBL
LigandPNGBDBM50277169(CHEMBL4166735)
Affinity DataIC50: 700nMAssay Description:Inhibition of recombinant mouse N-terminal FLAG-tagged Notch1 (1704 to 2531 residues) expressed in human LS174T cells assessed as reduction in doxycy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2020
Entry Details Article
PubMed