BDBM50277223 CHEMBL515245::rac-N-(2-(pyridin-2-ylmethylamino)-2,3-dihydro-1H-inden-5-yl)biphenyl-2-carboxamide

SMILES O=C(Nc1ccc2CC(Cc2c1)NCc1ccccn1)c1ccccc1-c1ccccc1

InChI Key InChIKey=VHIQFTOKJVJIJC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50277223   

TargetSmoothened homolog(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50277223(rac-N-(2-(pyridin-2-ylmethylamino)-2,3-dihydro-1H-...)
Affinity DataIC50: 1.15E+3nMAssay Description:Antagonist activity at human Smo receptor expressed in CHO cells by [3H]Hh-Ag binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50277223(rac-N-(2-(pyridin-2-ylmethylamino)-2,3-dihydro-1H-...)
Affinity DataIC50: 1.42E+3nMAssay Description:Antagonist activity at mouse Smo receptor expressed in CHO cells by [3H]Hh-Ag binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed