BDBM50277365 CHEMBL475709::N-(4-chlorophenyl)-4-(pyridin-4-ylmethylamino)isothiazole-3-carboxamide
SMILES Clc1ccc(NC(=O)c2nscc2NCc2ccncc2)cc1
InChI Key InChIKey=NYEXDGYOBOWOIP-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50277365
Affinity DataIC50: 140nMAssay Description:Inhibition of VEGFR2 assessed as blockade of pGAT-biotin phosphorylation in presence of 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of VEGFR1 assessed as blockade of pGAT-biotin phosphorylation in presence of 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Inhibition of VEGFR2 expressed in HEK293 cells assessed as inhibition of receptor phosphorylation by ELISAMore data for this Ligand-Target Pair
