BDBM50277399 CHEMBL4166863

SMILES COc1cccc(c1)-c1nc(Nc2ccc(cc2)[N+]([O-])=O)c2ccccc2n1

InChI Key InChIKey=MNKKGEXYUHWXJH-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50277399   

LigandPNGBDBM50277399(CHEMBL4166863)
Affinity DataEC50:  6nMAssay Description:Activation of ABCG2 ATPase activity (unknown origin) expressed in baculovirus infected high5 cell membranes after 20 mins by ascorbic acid ammonia mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2020
Entry Details Article
PubMed
LigandPNGBDBM50277399(CHEMBL4166863)
Affinity DataIC50: 66nMAssay Description:Inhibition of human GFP-fused ABCG2 expressed in MDCK2 cells assessed as reduction in Hoechst 33342 efflux preincubated for 30 mins followed by Hoech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2020
Entry Details Article
PubMed
LigandPNGBDBM50277399(CHEMBL4166863)
Affinity DataIC50: 68nMAssay Description:Inhibition of human GFP-fused ABCG2 expressed in MDCK2 cells assessed as reduction in Hoechst 33342 efflux preincubated for 30 mins followed by Hoech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2020
Entry Details Article
PubMed
LigandPNGBDBM50277399(CHEMBL4166863)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of ABCG2 ATPase activity (unknown origin) expressed in baculovirus infected high5 cell membranes after 20 mins by ascorbic acid ammonia mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2020
Entry Details Article
PubMed