BDBM50277422 CHEMBL4163316

SMILES COc1cccc(Nc2nc(nc3ccccc23)-c2ccc(cc2)[N+]([O-])=O)c1

InChI Key InChIKey=HKRNSYGZMDCKGV-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50277422   

LigandPNGBDBM50277422(CHEMBL4163316)
Affinity DataIC50: 107nMAssay Description:Inhibition of human GFP-fused ABCG2 expressed in MDCK2 cells assessed as reduction in Hoechst 33342 efflux preincubated for 30 mins followed by Hoech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2020
Entry Details Article
PubMed
LigandPNGBDBM50277422(CHEMBL4163316)
Affinity DataIC50: 107nMAssay Description:Inhibition of human GFP-fused ABCG2 expressed in MDCK2 cells assessed as reduction in Hoechst 33342 efflux preincubated for 30 mins followed by Hoech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2020
Entry Details Article
PubMed
LigandPNGBDBM50277422(CHEMBL4163316)
Affinity DataEC50:  239nMAssay Description:Activation of ABCG2 ATPase activity (unknown origin) expressed in baculovirus infected high5 cell membranes after 20 mins by ascorbic acid ammonia mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2020
Entry Details Article
PubMed