BDBM50277426 CHEMBL4172203

SMILES COc1ccc(cc1OC)-c1nc(Nc2ccc(O)c(c2)[N+]([O-])=O)c2ccccc2n1

InChI Key InChIKey=ZSTHOJTUHRHLBS-UHFFFAOYSA-N

Data  1 IC50  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50277426   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM50277426(CHEMBL4172203)Copy SMILESCopy InChI

Affinity DataEC50:  11nMAssay Description:Activation of ABCG2 ATPase activity (unknown origin) expressed in baculovirus infected high5 cell membranes after 20 mins by ascorbic acid ammonia mo...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/2/2020
Entry Details Article
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TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM50277426(CHEMBL4172203)Copy SMILESCopy InChI

Affinity DataIC50: 305nMAssay Description:Inhibition of human GFP-fused ABCG2 expressed in MDCK2 cells assessed as reduction in Hoechst 33342 efflux preincubated for 30 mins followed by Hoech...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/2/2020
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL