BDBM50277569 (4R,5S)-2-Acetyl-5-{(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}-4-(4-fluorophenyl)octahydro-1H-isoindole::CHEMBL484134

SMILES C[C@@H](O[C@H]1CC[C@@H]2CN(C[C@H]2[C@@H]1c1ccc(F)cc1)C(C)=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=QOJWQWHTTQNBIU-JONXPCGESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50277569   

TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277569((4R,5S)-2-Acetyl-5-{(1R)-1-[3,5-bis(trifluoromethy...)
Affinity DataIC50:  7.80nMAssay Description:Displacement of [125I]substance P human recombinant NK1 receptor expressed in CHO cells in presence of human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277569((4R,5S)-2-Acetyl-5-{(1R)-1-[3,5-bis(trifluoromethy...)
Affinity DataIC50:  0.110nMAssay Description:Displacement of [125I]substance P human recombinant NK1 receptor expressed in CHO cells in absence of human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed