BDBM50277652 CHEMBL4174269

SMILES COc1cc2CC(CC3CCN(Cc4cc(N)c5ccccc5n4)CC3)C(=O)c2cc1OC

InChI Key InChIKey=IVWHCJWPOJBTGB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50277652   

TargetAcetylcholinesterase(Homo sapiens (Human))
University Of S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50277652(CHEMBL4174269)
Affinity DataIC50:  710nMAssay Description:Binding affinity determined against ETA receptor in porcine aortic smooth muscle membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50277652(CHEMBL4174269)
Affinity DataIC50:  6.54E+3nMAssay Description:Inhibition of human serum BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured over 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed