BDBM50277795 2,4-dichloro-N-((4-(3-fluoropyridin-2-yl)-1-(1-methyl-1H-imidazol-4-ylsulfonyl)piperidin-4-yl)methyl)benzamide::CHEMBL482764

SMILES Cn1cnc(c1)S(=O)(=O)N1CCC(CNC(=O)c2ccc(Cl)cc2Cl)(CC1)c1ncccc1F

InChI Key InChIKey=VJAAPAVDSLDYMP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50277795   

TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277795(2,4-dichloro-N-((4-(3-fluoropyridin-2-yl)-1-(1-met...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human glycine transporter 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277795(2,4-dichloro-N-((4-(3-fluoropyridin-2-yl)-1-(1-met...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed