BDBM50277829 2,4-dichloro-N-((4-(3-fluoropyridin-2-yl)-1-(pyridin-3-ylsulfonyl)piperidin-4-yl)methyl)benzamide::CHEMBL485139

SMILES Fc1cccnc1C1(CNC(=O)c2ccc(Cl)cc2Cl)CCN(CC1)S(=O)(=O)c1cccnc1

InChI Key InChIKey=ZPNPSZYIFSSROO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50277829   

TargetSodium- and chloride-dependent glycine transporter 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277829(2,4-dichloro-N-((4-(3-fluoropyridin-2-yl)-1-(pyrid...)
Affinity DataIC50: 12nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed