BDBM50278007 (R)-3-((6-(2-fluoro-4-(trifluoromethoxy)phenyl)pyridin-3-yl)methyl)-5-methyloxazolidin-2-one::CHEMBL484956

SMILES C[C@@H]1CN(Cc2ccc(nc2)-c2ccc(OC(F)(F)F)cc2F)C(=O)O1

InChI Key InChIKey=HEEXJOMSNBMMTL-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50278007   

TargetMetabotropic glutamate receptor 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50278007((R)-3-((6-(2-fluoro-4-(trifluoromethoxy)phenyl)pyr...)
Affinity DataEC50:  380nMAssay Description:Agonist activity at mGluR2 expressed in HEK cells by FLIPR assay in presence of glutamateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50278007((R)-3-((6-(2-fluoro-4-(trifluoromethoxy)phenyl)pyr...)
Affinity DataKi: >3.10E+3nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed