BDBM50278041 2,4-dichloro-N-(((trans)-1-(cyclopropylmethyl)-4-(1-methyl-1H-1,2,3-triazol-4-ylsulfonyl)cyclohexyl)methyl)benzamide::CHEMBL482960

SMILES Cn1cc(nn1)S(=O)(=O)[C@H]1CC[C@@](CNC(=O)c2ccc(Cl)cc2Cl)(CC2CC2)CC1

InChI Key InChIKey=SLAWODYHZHIDLN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50278041   

TargetSodium- and chloride-dependent glycine transporter 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278041(2,4-dichloro-N-(((trans)-1-(cyclopropylmethyl)-4-(...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of [3H]glycine uptake at human glycine transporter 1 expressed in human JAR cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278041(2,4-dichloro-N-(((trans)-1-(cyclopropylmethyl)-4-(...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human GlyT1a after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed