BDBM50278358 1-(2-(4-(cyclohexylamino)pyrido[3,4-d]pyrimidin-6-yloxy)ethyl)pyrrolidin-2-one::CHEMBL471875

SMILES O=C1CCCN1CCOc1cc2c(NC3CCCCC3)ncnc2cn1

InChI Key InChIKey=QTADKBWBFMMERU-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278358   

TargetMetabotropic glutamate receptor 1(Rat)
Medical Research Council Technology

Curated by ChEMBL
LigandPNGBDBM50278358(1-(2-(4-(cyclohexylamino)pyrido[3,4-d]pyrimidin-6-...)
Affinity DataKi:  20nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed