BDBM50278527 6-(piperidin-4-ylmethoxy)-2-naphthonitrile::CHEMBL469552

SMILES N#Cc1ccc2cc(OCC3CCNCC3)ccc2c1

InChI Key InChIKey=SHJHTXWKDLOBQS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50278527   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50278527(6-(piperidin-4-ylmethoxy)-2-naphthonitrile | CHEMB...)
Affinity DataIC50: 15nMAssay Description:Inhibition of radiolabeled serotonin reuptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50278527(6-(piperidin-4-ylmethoxy)-2-naphthonitrile | CHEMB...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of radiolabeled noradrenaline reuptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50278527(6-(piperidin-4-ylmethoxy)-2-naphthonitrile | CHEMB...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of radiolabeled dopamine reuptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed