BDBM50278571 CHEMBL469997::N7-(3-chloro-4-fluorophenyl)-N2-phenylthiazolo[4,5-d]pyrimidine-2,7-diamine

SMILES Fc1ccc(Nc2ncnc3nc(Nc4ccccc4)sc23)cc1Cl

InChI Key InChIKey=VTPWWNYPRPJWNM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278571   

TargetEpidermal growth factor receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50278571(N7-(3-chloro-4-fluorophenyl)-N2-phenylthiazolo[4,5...)
Affinity DataIC50: 59nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed