BDBM50278663 CHEMBL4164660

SMILES C[C@H](COc1ccn(-c2ccc(F)cc2)c(=O)c1)Oc1ccccc1

InChI Key InChIKey=AUMJXOXUSGIUCB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50278663   

TargetMetabotropic glutamate receptor 3(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50278663(CHEMBL4164660)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of rat mGlu3R expressed in HEK cells harboring GIRK assessed as reduction in glutamate-induced thallium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50278663(CHEMBL4164660)
Affinity DataIC50: 3.00E+4nMAssay Description:Negative allosteric modulation of rat mGlu2 receptor expressed in HEK293 cells coexpressing Galpha15 assessed as inhibition of glutamate induced-calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50278663(CHEMBL4164660)
Affinity DataIC50: 3.00E+4nMAssay Description:Negative allosteric modulation of rat mGlu3 receptor expressed in TREX cells coexpressing Galpha15 assessed as inhibition of glutamate induced-calciu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2020
Entry Details Article
PubMed