BDBM50278676 (+/-)-cis-N-(4-((6-Amino-4-methylpyridin-2-yl)-methyl)-pyrrolidin-3-yl)-2-(3-fluorophenethylamino)-acetamide::CHEMBL470193

SMILES Cc1cc(N)nc(C[C@H]2CNC[C@H]2NC(=O)CNCCc2cccc(F)c2)c1

InChI Key InChIKey=ATHLQWRHZJQYBB-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50278676   

TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50278676((+/-)-cis-N-(4-((6-Amino-4-methylpyridin-2-yl)-met...)
Affinity DataKi:  53nMAssay Description:Inhibition of rat recombinant nNOS expressed in Escherichia coli assessed as nitric oxide formation by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50278676((+/-)-cis-N-(4-((6-Amino-4-methylpyridin-2-yl)-met...)
Affinity DataKi:  5.40E+3nMAssay Description:Inhibition of mouse recombinant iNOS expressed in Escherichia coli assessed as nitric oxide formation by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50278676((+/-)-cis-N-(4-((6-Amino-4-methylpyridin-2-yl)-met...)
Affinity DataKi:  2.70E+4nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli assessed as nitric oxide formation by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed