BDBM50278740 3-Hydroxy-6-methyl-4-thioxo-4H-pyran-2-carboxylic acid 4-methoxy-benzyl ester::CHEMBL470830

SMILES COc1ccc(CNC(=O)c2oc(C)cc(=S)c2O)cc1

InChI Key InChIKey=ABYNUYKRSMWNED-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50278740   

TargetStromelysin-1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50278740(3-Hydroxy-6-methyl-4-thioxo-4H-pyran-2-carboxylic ...)
Affinity DataIC50: 1.64E+4nMAssay Description:Inhibition of human MMP3 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50278740(3-Hydroxy-6-methyl-4-thioxo-4H-pyran-2-carboxylic ...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human MMP2 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50278740(3-Hydroxy-6-methyl-4-thioxo-4H-pyran-2-carboxylic ...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human MMP1 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed