BDBM50278745 (+/-)-cis-2-(4-((6-Amino-4-methylpyridin-2-yl)-methyl)-pyrrolidin-3-yloxy)-N-(3-fluorophenethyl)-acetamide::CHEMBL513702

SMILES Cc1cc(N)nc(C[C@H]2CNC[C@H]2OCC(=O)NCCc2cccc(F)c2)c1

InChI Key InChIKey=PZTBTGQUGHVYDA-QFBILLFUSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50278745   

TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50278745((+/-)-cis-2-(4-((6-Amino-4-methylpyridin-2-yl)-met...)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of rat recombinant nNOS expressed in Escherichia coli assessed as nitric oxide formation by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50278745((+/-)-cis-2-(4-((6-Amino-4-methylpyridin-2-yl)-met...)
Affinity DataKi:  5.20E+4nMAssay Description:Inhibition of mouse recombinant iNOS expressed in Escherichia coli assessed as nitric oxide formation by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50278745((+/-)-cis-2-(4-((6-Amino-4-methylpyridin-2-yl)-met...)
Affinity DataKi:  1.45E+5nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli assessed as nitric oxide formation by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed