BDBM50278812 5-Hydroxy-4-thioxo-4H-pyran-2-carboxylic acid (biphenyl-4-ylmethyl)-amide::CHEMBL523915

SMILES Oc1coc(cc1=S)C(=O)NCc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=FBFLGERGLQVEPE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50278812   

TargetStromelysin-1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50278812(5-Hydroxy-4-thioxo-4H-pyran-2-carboxylic acid (bip...)
Affinity DataIC50: 1.33E+4nMAssay Description:Inhibition of human MMP3 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50278812(5-Hydroxy-4-thioxo-4H-pyran-2-carboxylic acid (bip...)
Affinity DataIC50: 1.44E+4nMAssay Description:Inhibition of human MMP2 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50278812(5-Hydroxy-4-thioxo-4H-pyran-2-carboxylic acid (bip...)
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of human MMP1 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed