BDBM50278835 CHEMBL498052::N-((S)-1-amino-3-(2-fluorophenyl)propan-2-yl)-4-bromo-5-(1H-pyrrolo[2,3-b]pyridin-4-yl)thiophene-2-carboxamide

SMILES NC[C@H](Cc1ccccc1F)NC(=O)c1cc(Br)c(s1)-c1ccnc2[nH]ccc12

InChI Key InChIKey=RPLOLSBTEYRLOE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50278835   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278835(N-((S)-1-amino-3-(2-fluorophenyl)propan-2-yl)-4-br...)
Affinity DataIC50: 1nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278835(N-((S)-1-amino-3-(2-fluorophenyl)propan-2-yl)-4-br...)
Affinity DataIC50: 2nMAssay Description:Inhibition of AKT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278835(N-((S)-1-amino-3-(2-fluorophenyl)propan-2-yl)-4-br...)
Affinity DataIC50: 8nMAssay Description:Inhibition of AKT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed