BDBM50279458 CHEMBL4173072

SMILES FC(F)(F)Oc1ccc(NC(=O)Nc2ccc(cc2)-c2ccc(NC(=O)C=C)nc2)cc1

InChI Key InChIKey=JVUWVUOKZVOUHI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50279458   

TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50279458(CHEMBL4173072)
Affinity DataIC50: 60nMAssay Description:Inhibition of TIE-2 (unknown origin) after 4 hrs by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50279458(CHEMBL4173072)
Affinity DataIC50: 500nMAssay Description:Inhibition of VEGFR-2 (unknown origin) after 60 mins by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2020
Entry Details Article
PubMed