BDBM50279662 CHEMBL4163368

SMILES OB1OCc2ccc(NC(=O)Nc3ccccc3)cc12

InChI Key InChIKey=HAEGPUNQGVPWAR-UHFFFAOYSA-N

Data  9 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50279662   

TargetCarbonic anhydrase(Cryptococcus neoformans var. grubii (Filobasidiell...)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50279662BDBM50279662(CHEMBL4163368)
Affinity DataKi:  81nMAssay Description:Inhibition of Cryptococcus neoformans Can2 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase(Yeast)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50279662BDBM50279662(CHEMBL4163368)
Affinity DataKi:  86nMAssay Description:Inhibition of Candida glabrata Nce103 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50279662BDBM50279662(CHEMBL4163368)
Affinity DataKi:  240nMAssay Description:Inhibition of human carbonic anhydrase XII catalytic domain assessed as inhibition constant incubated for 15 to 360 mins by stopped-flow CO2 hydratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50279662BDBM50279662(CHEMBL4163368)
Affinity DataKi:  654nMAssay Description:Inhibition of human carbonic anhydrase-1 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50279662BDBM50279662(CHEMBL4163368)
Affinity DataKi:  654nMAssay Description:Inhibition of human carbonic anhydrase I assessed as inhibition constant incubated for 15 to 360 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50279662BDBM50279662(CHEMBL4163368)
Affinity DataKi:  730nMAssay Description:Inhibition of human carbonic anhydrase-2 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50279662BDBM50279662(CHEMBL4163368)
Affinity DataKi:  730nMAssay Description:Inhibition of human carbonic anhydrase 2 incubated for 30 mins prior to testing measured for 10 to 100 secs by phenol red-based stopped-flow CO2 hydr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50279662BDBM50279662(CHEMBL4163368)
Affinity DataKi:  730nMAssay Description:Inhibition of human carbonic anhydrase II assessed as inhibition constant incubated for 15 to 360 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50279662BDBM50279662(CHEMBL4163368)
Affinity DataKi:  1.06E+3nMAssay Description:Inhibition of human carbonic anhydrase IX catalytic domain assessed as inhibition constant incubated for 15 to 360 mins by stopped-flow CO2 hydration...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGenome polyprotein(DENV-2)
Heidelberg University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50279662BDBM50279662(CHEMBL4163368)
Affinity DataEC50:  2.25E+4nMAssay Description:Inhibition of full length DENV2 NS2B-NS3 protease in human HeLa cells expressing luciferase reporter gene incubated for 24 hrs by luminescence analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed