BDBM50279701 1-(6-ethoxy-2,3-dihydrochromen-4-ylideneamino)-3-(4-(4-methylpiperazin-1-yl)butyl)imidazolidine-2,4-dione::CHEMBL515594

SMILES CCOc1ccc2OCCC(=Nn3cc(O)n(CCCCN4CCN(C)CC4)c3=O)c2c1

InChI Key InChIKey=AUYIFUMXVZAUSA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50279701   

TargetPotassium voltage-gated channel subfamily H member 2(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279701(1-(6-ethoxy-2,3-dihydrochromen-4-ylideneamino)-3-(...)
Affinity DataIC50: 6.15E+3nMAssay Description:Inhibition of ERG in guinea pig ventricular myocytes assessed as blockade of rapid delayed rectifier potassium current by whole cell patch-clamp tech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279701(1-(6-ethoxy-2,3-dihydrochromen-4-ylideneamino)-3-(...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed