BDBM50279781 CHEMBL4162101

SMILES Clc1ccc2nc(NC3CCC3)nc(Nc3cc([nH]n3)C3CC3)c2c1

InChI Key InChIKey=ZHAXOKQWUHFBHX-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50279781   

TargetSerine/threonine-protein kinase PknB(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50279781(CHEMBL4162101)
Affinity DataKi:  72nMAssay Description:Inhibition of Mycobacterium tuberculosis PknB (M1 to G279 residues) expressed in Escherichia coli BL21 (DE3) cells using [T-33P]ATP as substrate afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details Article
PubMed