BDBM50280219 3-Benzenesulfonyl-2-benzyl-N-[(S)-1-((1S,2R,3S)-1-cyclohexylmethyl-2-hydroxy-3-methoxy-5-methyl-hexylcarbamoyl)-2-thiazol-4-yl-ethyl]-propionamide::CHEMBL30968

SMILES CO[C@@H](CC(C)C)[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1cscn1)NC(=O)C(Cc1ccccc1)CS(=O)(=O)c1ccccc1

InChI Key InChIKey=PJOKPPQHGIDJQG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50280219   

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50280219(3-Benzenesulfonyl-2-benzyl-N-[(S)-1-((1S,2R,3S)-1-...)
Affinity DataIC50: 0.770nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at PH 6.0More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50280219(3-Benzenesulfonyl-2-benzyl-N-[(S)-1-((1S,2R,3S)-1-...)
Affinity DataIC50: 18nMpH: 7.4Assay Description:In vitro inhibition of human plasma renin at PH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article