BDBM50280227 (1S,2R,3S)-2-(2-Morpholin-4-yl-2-oxo-ethyl)-3-phenyl-cyclopropanecarboxylic acid [(S)-1-((1S,2R,3S)-1-cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexylcarbamoyl)-2-thiazol-4-yl-ethyl]-amide::CHEMBL264848

SMILES CC(C)C[C@H](O)[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1cscn1)NC(=O)[C@H]1[C@H](CC(=O)N2CCOCC2)[C@@H]1c1ccccc1

InChI Key InChIKey=JQXCJBYPGPYAFB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50280227   

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50280227((1S,2R,3S)-2-(2-Morpholin-4-yl-2-oxo-ethyl)-3-phen...)
Affinity DataIC50: 0.700nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at PH 6.0More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50280227((1S,2R,3S)-2-(2-Morpholin-4-yl-2-oxo-ethyl)-3-phen...)
Affinity DataIC50: 20nMpH: 7.4Assay Description:In vitro inhibition of human plasma renin at PH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article