BDBM50280235 (1S,2S,3R)-2-Phenyl-3-(propane-2-sulfonyl)-cyclopropanecarboxylic acid [(S)-1-((1S,2R,3S)-1-cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexylcarbamoyl)-3-methyl-butyl]-amide::CHEMBL31121

SMILES CC(C)C[C@H](O)[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1[C@H]([C@H]1S(=O)(=O)C(C)C)c1ccccc1

InChI Key InChIKey=DTIIDFAAHDQNEL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50280235   

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50280235((1S,2S,3R)-2-Phenyl-3-(propane-2-sulfonyl)-cyclopr...)
Affinity DataIC50: 0.590nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at PH 6.0More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50280235((1S,2S,3R)-2-Phenyl-3-(propane-2-sulfonyl)-cyclopr...)
Affinity DataIC50: 14nMpH: 7.4Assay Description:In vitro inhibition of human plasma renin at PH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article