BDBM50280489 (S)-2-[(S)-3-(4-Methoxy-phenyl)-2-(3-methyl-butyrylamino)-propionylamino]-pentanoic acid ((S)-4-amino-1-cyclohexylmethyl-3,3-difluoro-2-oxo-butyl)-amide; hydrochloride::CHEMBL555920

SMILES CCC[C@H](NC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)CC(C)C)C(=O)N[C@@H](CC1CCCCC1)C(=O)C(F)(F)CN

InChI Key InChIKey=QNZBFRKAECKBST-GSDHBNRESA-N

Data  3 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50280489   

TargetChymotrypsinogen A(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50280489((S)-2-[(S)-3-(4-Methoxy-phenyl)-2-(3-methyl-butyry...)
Affinity DataKi:  2.50E+3nMAssay Description:Concentration required to inhibit the enzyme chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCathepsin S(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50280489((S)-2-[(S)-3-(4-Methoxy-phenyl)-2-(3-methyl-butyry...)
Affinity DataKi:  4.00E+3nMAssay Description:Concentration required to inhibit the enzyme cathepsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPepsin A(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50280489((S)-2-[(S)-3-(4-Methoxy-phenyl)-2-(3-methyl-butyry...)
Affinity DataKi:  4.00E+4nMAssay Description:Concentration required to inhibit the enzyme pepsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50280489((S)-2-[(S)-3-(4-Methoxy-phenyl)-2-(3-methyl-butyry...)
Affinity DataIC50:  16nMAssay Description:Concentration of the compound required to inhibit human plasma renin by 50% using radio-immunoassay was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50280489((S)-2-[(S)-3-(4-Methoxy-phenyl)-2-(3-methyl-butyry...)
Affinity DataIC50:  22nMAssay Description:Evaluated for the antagonistic activity against 5-hydroxytryptamine 3 receptor in isolated perfused rabbit heart (RH)More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50280489((S)-2-[(S)-3-(4-Methoxy-phenyl)-2-(3-methyl-butyry...)
Affinity DataIC50:  3.00E+3nMAssay Description:Evaluated for the antagonistic activity against 5-hydroxytryptamine 3 receptor in isolated guinea pig ileum (GPI)More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50280489((S)-2-[(S)-3-(4-Methoxy-phenyl)-2-(3-methyl-butyry...)
Affinity DataIC50:  1.00E+5nMAssay Description:Concentration of the compound required to inhibit rat plasma renin by 50% using radio-immunoassay was determinedMore data for this Ligand-Target Pair
In DepthDetails Article