BDBM50281005 CHEMBL76445::[(5R,6S)-7-Oxo-6-((R)-1-phenylacetoxy-ethyl)-2,4-dithia-1-aza-bicyclo[3.2.0]hept-(3E)-ylidene]-acetic acid tert-butyl ester

SMILES C[C@@H](OC(=O)Cc1ccccc1)[C@@H]1[C@H]2S\C(SN2C1=O)=C/C(=O)OC(C)(C)C

InChI Key InChIKey=JNSCESNWTXEGCI-UHFFFAOYSA-N

Data  1 KI  1 Koff  1 Kon

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50281005   

TargetNeutrophil elastase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50281005([(5R,6S)-7-Oxo-6-((R)-1-phenylacetoxy-ethyl)-2,4-d...)
Affinity DataKi:  400nMAssay Description:Inhibitory activity against human leukocyte elastase (HLE) was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetNeutrophil elastase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50281005([(5R,6S)-7-Oxo-6-((R)-1-phenylacetoxy-ethyl)-2,4-d...)
Affinity DataKon:  0.000400M-1s-1Assay Description:Rate constant for the compound was determined (k2/ki) against human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetNeutrophil elastase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50281005([(5R,6S)-7-Oxo-6-((R)-1-phenylacetoxy-ethyl)-2,4-d...)
Affinity DataKoff:  970s-1Assay Description:Rate constant for the compound was determined (k2/ki) against human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article