BDBM50281296 CHEMBL4173626

SMILES CCc1ccc(o1)-c1cc(NC2CCN(CC2)C(C)C)c2cc(OC)c(OCCCN3CCCC3)cc2n1

InChI Key InChIKey=USIHDOVZZRFRAY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50281296   

TargetHistone-lysine N-methyltransferase EHMT2(Human)
Universidad De Oviedo-Principado De Asturias

Curated by ChEMBL
LigandPNGBDBM50281296(CHEMBL4173626)
Affinity DataIC50: 3nMAssay Description:Inhibition of human G9a using biotinylated-H3K9 peptide as substrate after 1 hr in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2020
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Universidad De Oviedo-Principado De Asturias

Curated by ChEMBL
LigandPNGBDBM50281296(CHEMBL4173626)
Affinity DataIC50: 284nMAssay Description:Inhibition of human DNMT1 using polydeoxyinosine polydeoxycytosine DNA as substrate after 15 mins in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2020
Entry Details Article
PubMed