BDBM50281321 CHEMBL4173662

SMILES COc1cc2c(NC3CCN(C)CC3)cc(nc2cc1OCCCN1CCCC1)-c1ccoc1

InChI Key InChIKey=GXAJALCTHNRXSM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50281321   

TargetHistone-lysine N-methyltransferase EHMT2(Human)
Universidad De Oviedo-Principado De Asturias

Curated by ChEMBL
LigandPNGBDBM50281321(CHEMBL4173662)
Affinity DataIC50: 7nMAssay Description:Inhibition of human G9a using biotinylated-H3K9 peptide as substrate after 1 hr in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2020
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Universidad De Oviedo-Principado De Asturias

Curated by ChEMBL
LigandPNGBDBM50281321(CHEMBL4173662)
Affinity DataIC50: 978nMAssay Description:Inhibition of human DNMT1 using polydeoxyinosine polydeoxycytosine DNA as substrate after 15 mins in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2020
Entry Details Article
PubMed