BDBM50281340 5-{[(2-Chloro-ethyl)-ethyl-amino]-methyl}-3,3-diphenyl-dihydro-furan-2-one::CHEMBL98987

SMILES CCN(CCCl)CC1CC(C(=O)O1)(c1ccccc1)c1ccccc1

InChI Key InChIKey=KXAHVZWNLQSGOP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50281340   

TargetEnvelope glycoprotein gp160(HIV-1)
TBA

Curated by ChEMBL
LigandPNGBDBM50281340(5-{[(2-Chloro-ethyl)-ethyl-amino]-methyl}-3,3-diph...)
Affinity DataIC50: 3.00E+4nMAssay Description:Tested for ability to block the CD4-gp120 interaction measured by binding of [125I]sCD4 to gp120More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetEnvelope glycoprotein gp160(HIV-1)
TBA

Curated by ChEMBL
LigandPNGBDBM50281340(5-{[(2-Chloro-ethyl)-ethyl-amino]-methyl}-3,3-diph...)
Affinity DataIC50: 3.00E+4nMAssay Description:Tested for ability to block the CD4-gp120 interaction measured by binding of [125I]sCD4 to gp120More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetEnvelope glycoprotein gp160(HIV-1)
TBA

Curated by ChEMBL
LigandPNGBDBM50281340(5-{[(2-Chloro-ethyl)-ethyl-amino]-methyl}-3,3-diph...)
Affinity DataIC50: 1.00E+5nMAssay Description:Tested in an HIV viral syncytium assay for inhibition of binding of recombinant CD4-gp120More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article