BDBM50282225 DISCORHABDIN B

SMILES [H][C@@]12C[C@]3(C=C(Br)C(=O)C=C3S1)C1=C(N2)C(=O)c2[nH]cc3CCN=C1c23

InChI Key InChIKey=SVKKMXJIWIOCJC-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50282225   

TargetAcetylcholinesterase(Electric eel)
University of Maribor

Curated by ChEMBL
LigandPNGBDBM50282225(DISCORHABDIN B)
Affinity DataKi:  1.90E+3nMAssay Description:Reversible competitive inhibition of electric eel AChE using acetylthiocholine iodide as substrate measured over 5 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Maribor

Curated by ChEMBL
LigandPNGBDBM50282225(DISCORHABDIN B)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate measured over 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Maribor

Curated by ChEMBL
LigandPNGBDBM50282225(DISCORHABDIN B)
Affinity DataKi:  2.28E+4nMAssay Description:Reversible competitive inhibition of human AChE using acetylthiocholine iodide as substrate measured over 5 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Maribor

Curated by ChEMBL
LigandPNGBDBM50282225(DISCORHABDIN B)
Affinity DataIC50: 4.94E+4nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate measured over 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2020
Entry Details Article
PubMed
TargetCholinesterase(Horse)
University of Maribor

Curated by ChEMBL
LigandPNGBDBM50282225(DISCORHABDIN B)
Affinity DataKi:  7.60E+4nMAssay Description:Inhibition of equine serum BChE using acetylthiocholine iodide as substrate measured over 5 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2020
Entry Details Article
PubMed
TargetCholinesterase(Horse)
University of Maribor

Curated by ChEMBL
LigandPNGBDBM50282225(DISCORHABDIN B)
Affinity DataIC50: 1.37E+5nMAssay Description:Reversible competitive inhibition of equine serum BChE using acetylthiocholine iodide as substrate measured over 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2020
Entry Details Article
PubMed