BDBM50283269 CHEMBL4175949

SMILES Nc1n[nH]c2cccc(-c3ccc(NC(=S)Nc4ccc(Cl)cc4Cl)cc3)c12

InChI Key InChIKey=ANJMTRKKSQNBTH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50283269   

TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50283269(CHEMBL4175949)
Affinity DataIC50: 20nMAssay Description:Inhibition of TIE2 (unknown origin) after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2020
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50283269(CHEMBL4175949)
Affinity DataIC50: 21nMAssay Description:Inhibition of EPHB4 (unknown origin) after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50283269(CHEMBL4175949)
Affinity DataIC50: 24nMAssay Description:Inhibition of VEGFR2 (unknown origin) using Poly E4Y1 substrate after 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2020
Entry Details Article
PubMed