BDBM50284034 (2R,6R)-2,6-Dibenzyl-4-hydroxy-heptanedioic acid bis-({(1S,2S)-2-[(isoquinoline-3-carbonyl)-amino]-cyclohexyl}-amide)::CHEMBL348047

SMILES OC(C[C@@H](Cc1ccccc1)C(=O)N[C@H]1CCCC[C@@H]1NC(=O)c1cc2ccccc2cn1)C[C@@H](Cc1ccccc1)C(=O)N[C@H]1CCCC[C@@H]1NC(=O)c1cc2ccccc2cn1

InChI Key InChIKey=OFDHFSOXKZFXTL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50284034   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50284034((2R,6R)-2,6-Dibenzyl-4-hydroxy-heptanedioic acid b...)
Affinity DataIC50: 45nMAssay Description:Compound was tested for inhibitory activity against recombinant HIV-1 protease using 125 I-SPA (scintillation proximity assay)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article