BDBM50284615 2-Benzyl-3-(3,5-bis-trifluoromethyl-benzyloxy)-1-aza-bicyclo[2.2.2]octane::CHEMBL282657

SMILES FC(F)(F)c1cc(CO[C@H]2C3CCN(CC3)[C@H]2Cc2ccccc2)cc(c1)C(F)(F)F

InChI Key InChIKey=JOTMNMNWQYWMOE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50284615   

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284615(2-Benzyl-3-(3,5-bis-trifluoromethyl-benzyloxy)-1-a...)
Affinity DataIC50: 197nMAssay Description:Binding affinity towards wild type human Wild-type tachykinin receptor 1 expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284615(2-Benzyl-3-(3,5-bis-trifluoromethyl-benzyloxy)-1-a...)
Affinity DataIC50: 500nMAssay Description:Binding affinity towards human mutant NK-1 receptor in which His-197 has been replaced by alanine (H197A)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article