BDBM50286101 CHEMBL3037845::Morphinan Cyclic Imine analogue

SMILES [H][C@@]12N=C(c3ccccc3)[C@]3(C)C[C@]4(C=C[C@]13OC)[C@@]1([H])Cc3ccc(OC)c(OC)c3[C@@]24CC[N+]1(C)C

InChI Key InChIKey=DOHPOTFCTOJIQG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50286101   

TargetMu-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50286101(Morphinan Cyclic Imine analogue | CHEMBL3037845)
Affinity DataIC50: 0.560nMAssay Description:Compound was tested for its ability to displace [3H]DAMGO from mu opioid receptor in hartley guinea pig brain membrane in the presence of 100 nM of D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetKappa-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50286101(Morphinan Cyclic Imine analogue | CHEMBL3037845)
Affinity DataIC50: 4.70nMAssay Description:Compound was tested for its ability to displace bremazocine from Opioid receptor kappa 2 in hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetDelta-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286101(Morphinan Cyclic Imine analogue | CHEMBL3037845)
Affinity DataIC50: 34nMAssay Description:Compound was tested for its ability to displace [3H]Cl-DPDPE from delta opioid receptor in hartley guinea pig brain membrane in the presence of 100 n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetKappa-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50286101(Morphinan Cyclic Imine analogue | CHEMBL3037845)
Affinity DataIC50: 380nMAssay Description:Compound was tested for its ability to displace bremazocine from Opioid receptor kappa 2 in hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article